Note: The number of original episodes remaining this season appears after each show title.
| March 2008 | ||||||
| Sun | Mon | Tue | Wed | Thu | Fri | Sat |
| 16 | 17 | 18 | 19 | 20 | 21 | 22 |
| How I Met … (7) | ||||||
| Big Bang Theory (7) | ||||||
| Two and 1/2 Men (7) | ||||||
| 23 | 24 | 25 | 26 | 27 | 28 | 29 |
| CSI Miami (7) | Til Death (6) | |||||
| April 2008 | ||||||
| Sun | Mon | Tue | Wed | Thu | Fri | Sat |
| 30-Mar | 31-Mar | 1 | 2 | 3 | 4 | 5 |
| Cold Case (4) | Criminal Minds (7) | CSI (6) | Ghost Whisperer (6) | |||
| CSI NY (7) | Without a Trace (6) | Numb3rs (6) | ||||
| My Name is Earl (9) | ||||||
| 6 | 7 | 8 | 9 | 10 | 11 | 12 |
| Samantha Who? (6) | Boston Legal (6) | ER (6) | ||||
| NCIS (7) | 30 Rock (5) | |||||
| The Office (6) | ||||||
| Scrubs (5) | ||||||
| 13 | 14 | 15 | 16 | 17 | 18 | 19 |
| Desperate Housewives (5 + 2 hr. finale) | Bones (6) | L&O SVU (5) | Back to You (5) | Smallville (5) | ||
| One Tree Hill (6) | Til Death (5) | |||||
| Rules of Engagement (6) | ||||||
| 20 | 21 | 22 | 23 | 24 | 25 | 26 |
| Brothers and Sisters (4) | Gossip Girl (5) | Reaper (5) | Law and Order (5) | Ugly Betty (5) | Moonlight (4) | |
| Grey's Anatomy (5) | ||||||
| Lost (5) | ||||||
| Supernatural (4) | ||||||
| 27 | 28 | 29 | 30 | |||
| Aliens in America (4) | House (4) | Shark (4) | ||||
| Color Code: | ABC | CBS | NBC | FOX | CW | |